LMPD Database

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LMP002700

UniProt Annotations

Entry Information
Gene Nameprostaglandin D2 receptor (DP)
Protein EntryQ13258_HUMAN
UniProt IDQ13258
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q13258-1; Sequence=Displayed; Name=2; IsoId=Q13258-2; Sequence=VSP_055141, VSP_055142; Note=No experimental confirmation available. Derived from EST data.;
DiseaseAsthma-related traits 1 (ASRT1) [MIM
FunctionReceptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity).
SimilarityBelongs to the G-protein coupled receptor 1 family.
Subcellular LocationCell membrane ; Multi-pass membrane protein .
Tissue SpecificityExpressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes. {ECO
Web ResourceName=SeattleSNPs; URL="http://pga.gs.washington.edu/data/apobec3f/";