LMPD Database

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LMP002831

UniProt Annotations

Entry Information
Gene Namecysteinyl leukotriene receptor 2
Protein EntryCLTR2_MOUSE
UniProt IDQ920A1
SpeciesMouse
Comments
Comment typeDescription
FunctionReceptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.
SimilarityBelongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}.
Subcellular LocationCell membrane; Multi-pass membrane protein.
Tissue SpecificityWidely expressed at low levels, with highest expression in the spleen, thymus and adrenal gland, and lower in the kidney, brain and peripheral blood leukocytes.