LMPD Database

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LMP002969

UniProt Annotations

Entry Information
Gene Namearylsulfatase G
Protein EntryARSG_MOUSE
UniProt IDQ3TYD4
SpeciesMouse
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q3TYD4-1; Sequence=Displayed; Name=2; IsoId=Q3TYD4-2; Sequence=VSP_018628, VSP_018629; Note=No experimental confirmation available.;
CofactorName=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Note=Binds 1 Ca(2+) ion per subunit. {ECO:0000250};
FunctionDisplays arylsulfatase activity with pseudosubstrates at acidic pH, such as p-nitrocatechol sulfate. {ECO:0000250}.
PtmGlycosylated. {ECO:0000250}.
PtmN-glycosylated. {ECO:0000250}.
PtmThe conversion to 3-oxoalanine (also known as C- formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. {ECO:0000250}.
SimilarityBelongs to the sulfatase family. {ECO:0000305}.
Subcellular LocationLysosome. Note=Previously observed endoplasmic reticulum localization is most likely due to folding/maturation problems for overexpressed proteins. {ECO:0000250}.