LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP002981

UniProt Annotations

Entry Information
Gene NameUDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
Protein EntryB3GT2_HUMAN
UniProt IDO43825
SpeciesHuman
Comments
Comment typeDescription
CofactorName=Mn(2+); Xref=ChEBI
FunctionBeta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 31 family.
Subcellular LocationGolgi apparatus membrane ; Single-pass type II membrane protein .
Tissue SpecificityDetected in heart and brain.
Web ResourceName=Functional Glycomics Gateway - GTase; Note=Beta-1,3-galactosyltransferase 2; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_430";
Web ResourceName=GGDB; Note=GlycoGene database; URL="http://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B3GALT2";