LMPD Database

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LMP005421

UniProt Annotations

Entry Information
Gene Namemyo-inositol oxygenase
Protein EntryMIOX_MOUSE
UniProt IDQ9QXN5
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityMyo-inositol + O(2) = D-glucuronate + H(2)O.
CofactorName=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000269|PubMed:17012379, ECO:0000269|PubMed:18364358}; Note=Binds 2 iron ions per subunit. {ECO:0000269|PubMed:17012379, ECO:0000269|PubMed:18364358};
PathwayPolyol metabolism; myo-inositol degradation into D- glucuronate; D-glucuronate from myo-inositol: step 1/1.
SimilarityBelongs to the myo-inositol oxygenase family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000250}.
Tissue SpecificityKidney specific. Renal proximal tubules. {ECO:0000269|PubMed:10944187}.