LMPD Database

LMP006705

Gene Information

Entrez Gene ID	5320
Gene Name	phospholipase A2, group IIA (platelets, synovial fluid)
Gene Symbol	PLA2G2A
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005783	IDA:LIFEdb	C	endoplasmic reticulum
GO:0005789	TAS:Reactome	C	endoplasmic reticulum membrane
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	IDA:BHF-UCL	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005739	IEA:Ensembl	C	mitochondrion
GO:0030141	IEA:Ensembl	C	secretory granule
GO:0047498	TAS:UniProtKB	F	calcium-dependent phospholipase A2 activity
GO:0005509	IEA:InterPro	F	calcium ion binding
GO:0004623	IDA:BHF-UCL	F	phospholipase A2 activity
GO:0005543	IDA:BHF-UCL	F	phospholipid binding
GO:0050830	TAS:BHF-UCL	P	defense response to Gram-positive bacterium
GO:0046474	TAS:Reactome	P	glycerophospholipid biosynthetic process
GO:0016042	IEA:UniProtKB-KW	P	lipid catabolic process
GO:0034374	TAS:BHF-UCL	P	low-density lipoprotein particle remodeling
GO:0050680	IEA:Ensembl	P	negative regulation of epithelial cell proliferation
GO:0006654	TAS:Reactome	P	phosphatidic acid biosynthetic process
GO:0046473	IDA:BHF-UCL	P	phosphatidic acid metabolic process
GO:0036151	TAS:Reactome	P	phosphatidylcholine acyl-chain remodeling
GO:0036152	TAS:Reactome	P	phosphatidylethanolamine acyl-chain remodeling
GO:0036148	TAS:Reactome	P	phosphatidylglycerol acyl-chain remodeling
GO:0036149	TAS:Reactome	P	phosphatidylinositol acyl-chain remodeling
GO:0036150	TAS:Reactome	P	phosphatidylserine acyl-chain remodeling
GO:0006644	IDA:BHF-UCL	P	phospholipid metabolic process
GO:0050729	TAS:BHF-UCL	P	positive regulation of inflammatory response
GO:0010744	TAS:BHF-UCL	P	positive regulation of macrophage derived foam cell differentiation
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0035019	IEA:Ensembl	P	somatic stem cell maintenance

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04014	Ras signaling pathway