LMPD Database

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LMP006772

Gene Information

Entrez Gene ID8644
Gene Namealdo-keto reductase family 1, member C3
Gene SymbolAKR1C3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005622 IDA:LIFEdbCintracellular
GO:0005634 IDA:UniProtKBCnucleus
GO:0047020 IDA:UniProtKBF15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
GO:0004032 IDA:UniProtKBFalditol:NADP+ 1-oxidoreductase activity
GO:0004033 TAS:UniProtKBFaldo-keto reductase (NADP) activity
GO:0047023 IDA:UniProtKBFandrosterone dehydrogenase activity
GO:0047787 IDA:UniProtKBFdelta4-3-oxosteroid 5beta-reductase activity
GO:0035410 IDA:UniProtKBFdihydrotestosterone 17-beta-dehydrogenase activity
GO:0045550 IDA:UniProtKBFgeranylgeranyl reductase activity
GO:0047718 IEA:UniProtKB-ECFindanol dehydrogenase activity
GO:0045703 IDA:UniProtKBFketoreductase activity
GO:0047086 IDA:UniProtKBFketosteroid monooxygenase activity
GO:0016655 IDA:UniProtKBFoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0018636 IDA:UniProtKBFphenanthrene 9,10-monooxygenase activity
GO:0036131 IEA:UniProtKB-ECFprostaglandin D2 11-ketoreductase activity
GO:0004958 IDA:UniProtKBFprostaglandin F receptor activity
GO:0047017 IEA:UniProtKB-ECFprostaglandin-F synthase activity
GO:0001758 IDA:UniProtKBFretinal dehydrogenase activity
GO:0004745 IDA:UniProtKBFretinol dehydrogenase activity
GO:0047045 IEA:UniProtKB-ECFtestosterone 17-beta-dehydrogenase (NADP+) activity
GO:0047035 IEA:UniProtKB-ECFtestosterone dehydrogenase (NAD+) activity
GO:0047115 IEA:UniProtKB-ECFtrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0071276 IDA:UniProtKBPcellular response to cadmium ion
GO:0071277 IDA:UniProtKBPcellular response to calcium ion
GO:0071384 IDA:UniProtKBPcellular response to corticosteroid stimulus
GO:0071395 IDA:UniProtKBPcellular response to jasmonic acid stimulus
GO:0071379 IDA:UniProtKBPcellular response to prostaglandin stimulus
GO:0034614 IDA:UniProtKBPcellular response to reactive oxygen species
GO:0009267 IEP:UniProtKBPcellular response to starvation
GO:0019371 TAS:ReactomePcyclooxygenase pathway
GO:0044597 IMP:UniProtKBPdaunorubicin metabolic process
GO:0044598 IMP:UniProtKBPdoxorubicin metabolic process
GO:0016488 IDA:UniProtKBPfarnesol catabolic process
GO:0007186 IDA:UniProtKBPG-protein coupled receptor signaling pathway
GO:0030216 IEP:UniProtKBPkeratinocyte differentiation
GO:0008584 IEP:UniProtKBPmale gonad development
GO:0044259 IEP:UniProtKBPmulticellular organismal macromolecule metabolic process
GO:1900053 IDA:UniProtKBPnegative regulation of retinoic acid biosynthetic process
GO:0055114 IDA:UniProtKBPoxidation-reduction process
GO:0007603 TAS:ReactomePphototransduction, visible light
GO:0010942 IDA:UniProtKBPpositive regulation of cell death
GO:0008284 IDA:UniProtKBPpositive regulation of cell proliferation
GO:2000353 IDA:UniProtKBPpositive regulation of endothelial cell apoptotic process
GO:0051897 IDA:UniProtKBPpositive regulation of protein kinase B signaling
GO:2000379 IDA:UniProtKBPpositive regulation of reactive oxygen species metabolic process
GO:0042448 IDA:UniProtKBPprogesterone metabolic process
GO:0006693 IEP:UniProtKBPprostaglandin metabolic process
GO:0000060 IDA:UniProtKBPprotein import into nucleus, translocation
GO:0048385 IDA:UniProtKBPregulation of retinoic acid receptor signaling pathway
GO:2000224 IMP:UniProtKBPregulation of testosterone biosynthetic process
GO:0070293 NAS:UniProtKBPrenal absorption
GO:0007584 IEP:UniProtKBPresponse to nutrient
GO:0034694 IDA:UniProtKBPresponse to prostaglandin
GO:0042574 IDA:UniProtKBPretinal metabolic process
GO:0001523 TAS:ReactomePretinoid metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0008202 IEP:UniProtKBPsteroid metabolic process
GO:0061370 IMP:UniProtKBPtestosterone biosynthetic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04913Ovarian steroidogenesis
hsa00140Steroid hormone biosynthesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150149Synthesis of Prostaglandins (PG) and Thromboxanes (TX)