LMPD Database

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LMP006844

UniProt Annotations

Entry Information
Gene Namealdo-keto reductase superfamily protein
Protein EntryKAR_YEAST
UniProt IDQ07551
SpeciesYeast (S288c)
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=146 uM for o-chlorobenzoylformamide {ECO:0000269|PubMed:15564669}; KM=156 uM for m-chlorobenzoylformamide {ECO:0000269|PubMed:15564669}; KM=231 uM for p-chlorobenzoylformamide {ECO:0000269|PubMed:15564669}; KM=103 uM for benzoylformamide {ECO:0000269|PubMed:15564669}; KM=254 uM for 3-methyl-2-oxobutanoate {ECO:0000269|PubMed:15564669}; pH dependence: Stable from pH 6 to 9.5. {ECO:0000269|PubMed:15564669}; Temperature dependence: Thermostable up to 40 degrees Celsius. {ECO:0000269|PubMed:15564669};
FunctionReduces aromatic alpha-keto amides, aliphatic and aromatic alpha-keto esters, but not beta-keto esters. {ECO:0000269|PubMed:11306085}.
InductionTransiently induced shortly after the switch from aerobic to anaerobic growth (at protein level). {ECO:0000269|PubMed:12627397}.
MiscellaneousPresent with 4030 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PtmThe N-terminus is blocked.
SimilarityBelongs to the aldo/keto reductase family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
SubunitMonomer. {ECO:0000269|PubMed:15564669}.