LMPD Database

LMP006851

UniProt Annotations

Entry Information
Gene NameNcr1p
Protein EntryNPC1_YEAST
UniProt IDQ12200
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionInvolved in sphingolipid trafficking. May recycle sphingolipids between cellular membranous compartments. {ECO:0000269|PubMed:14970192, ECO:0000269|PubMed:16138904}.
MiscellaneousPresent with 521 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the patched family. {ECO:0000305}.
SimilarityContains 1 SSD (sterol-sensing) domain. {ECO:0000255|PROSITE-ProRule:PRU00199}.
Subcellular LocationVacuole membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14970192, ECO:0000269|PubMed:15522102}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14970192, ECO:0000269|PubMed:15522102}.