LMPD Database

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LMP006869

UniProt Annotations

Entry Information
Gene NameC-8 sterol isomerase ERG2
Protein EntryERG2_YEAST
UniProt IDP32352
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionCatalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
MiscellaneousPresent with 2640 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
MiscellaneousThis protein is a major target of morpholine antibiotics.
PathwaySteroid metabolism; ergosterol biosynthesis; ergosterol from zymosterol: step 2/5.
SimilarityBelongs to the ERG2 family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.