LMPD Database

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LMP006873

UniProt Annotations

Entry Information
Gene NamePer1p
Protein EntryPER1_YEAST
UniProt IDP25625
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionInvolved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI. Required for efficient transport of GPI-anchor proteins. {ECO:0000269|PubMed:17021251}.
MiscellaneousPresent with 3050 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the PGAP3/PER1 family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17021251}; Multi- pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17021251}.