LMPD Database

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LMP006876

UniProt Annotations

Entry Information
Gene NameEtr1p
Protein EntryETR1_YEAST
UniProt IDP38071
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + NADP(+) = trans-2,3-dehydroacyl-CoA + NADPH.
Catalytic ActivityAn acyl-[acyl-carrier protein] + NADP(+) = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH.
CautionWas originally (PubMed:8195160) thought to be a nuclear protein involved in transcriptional regulation of genes required for the functional assembly of mitochondrial respiratory proteins. This was later proven not to be the case (PubMed:11509667)
CautionWas originally (PubMed:8195160) thought to be a nuclear protein involved in transcriptional regulation of genes required for the functional assembly of mitochondrial respiratory proteins. This was later proven not to be the case (PubMed:11509667). {ECO:0000305|PubMed:11509667, ECO:0000305|PubMed:8195160}.
FunctionRequired for respiration and the maintenance of the mitochondrial compartment. Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2-decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis
FunctionRequired for respiration and the maintenance of the mitochondrial compartment. Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2-decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis. {ECO:0000269|PubMed:11509667, ECO:0000269|PubMed:12614607}.
MiscellaneousPresent with 1560 molecules/cell in log phase SD medium
MiscellaneousPresent with 1560 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
SimilarityBelongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. {ECO:0000305}.
Subcellular LocationMitochondrion matrix {ECO:0000269|PubMed:11502169, ECO:0000269|PubMed:11509667, ECO:0000269|PubMed:14576278}.
SubunitHomodimer or in a complex with other proteins. Interacts with ARS1
SubunitHomodimer or in a complex with other proteins. Interacts with ARS1. {ECO:0000269|PubMed:11509667}.