LMPD Database

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LMP006888

UniProt Annotations

Entry Information
Gene Namebifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase
Protein EntryFPPS_YEAST
UniProt IDP08524
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityDimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
Catalytic ActivityGeranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)-farnesyl diphosphate.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 3 Mg(2+) ions per subunit. {ECO:0000250};
FunctionCatalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
PathwayIsoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
PathwayIsoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
SimilarityBelongs to the FPP/GGPP synthase family. {ECO:0000305}.
Subcellular LocationCytoplasm.