LMPD Database

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LMP006905

UniProt Annotations

Entry Information
Gene NameSmp3p
Protein EntrySMP3_YEAST
UniProt IDQ04174
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionAlpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is essential in fungi. Involved in plasmid maintenance with SMP2
FunctionAlpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is essential in fungi. Involved in plasmid maintenance with SMP2. {ECO:0000269|PubMed:11356840}.
InteractionP36156:ECM4; NbExp=1; IntAct=EBI-2089413, EBI-2042717;
PathwayGlycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
SimilarityBelongs to the glycosyltransferase 22 family. PIGZ subfamily
SimilarityBelongs to the glycosyltransferase 22 family. PIGZ subfamily. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein .
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.