LMPD Database

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LMP006920

UniProt Annotations

Entry Information
Gene NameGpi2p
Protein EntryGPI2_YEAST
UniProt IDP46961
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityUDP-N-acetyl-D-glucosamine + 1-phosphatidyl- 1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1- phosphatidyl-1D-myo-inositol.
FunctionPart of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
InteractionP62651:ERI1; NbExp=1; IntAct=EBI-7809, EBI-975247; Q04082:GPI19; NbExp=1; IntAct=EBI-7809, EBI-36611; P01120:RAS2; NbExp=1; IntAct=EBI-7809, EBI-14838;
PathwayGlycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
SimilarityBelongs to the PIGC family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
SubunitComponent of a complex with GPI1, GPI2, GPI3, GPI15 and ERI1 (Probable). Interacts with ERI1. {ECO:0000269|PubMed:15163411, ECO:0000305}.