LMPD Database

LMP006948

UniProt Annotations

Entry Information
Gene NameAcp1p
Protein EntryACPM_YEAST
UniProt IDP32463
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionCarrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). May be involved in the synthesis of very-long-chain fatty acids. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity). {ECO:0000250}.
MiscellaneousPresent with 60500 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayLipid metabolism; fatty acid biosynthesis.
Ptm4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group (By similarity). {ECO:0000250}.
SimilarityContains 1 acyl carrier domain. {ECO:0000305}.
Subcellular LocationMitochondrion.
SubunitComplex I is composed of about 30 different subunits.