LMPD Database

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LMP006975

UniProt Annotations

Entry Information
Gene NameF0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP2
Protein EntryATP9_YEAST
UniProt IDP61829
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionMitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
SimilarityBelongs to the ATPase C chain family
SimilarityBelongs to the ATPase C chain family. {ECO:0000305}.
Subcellular LocationMitochondrion membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}.
Subcellular LocationMitochondrion membrane ; Multi- pass membrane protein .
SubunitF-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.