LMPD Database

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LMP006978

UniProt Annotations

Entry Information
Gene Nameaminophospholipid-translocating P4-type ATPase DRS2
Protein EntryATC3_YEAST
UniProt IDP39524
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).
FunctionThis magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of phospholipids (Potential). Seems to be involved in ribosome assembly. {ECO:0000305}.
MiscellaneousPresent with 606 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. {ECO:0000305}.
Subcellular LocationGolgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:12372257, ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:12372257, ECO:0000269|PubMed:14562095}.
SubunitInteracts with CDC50. {ECO:0000269|PubMed:15090616}.