LMPD Database

LMP006982

UniProt Annotations

Entry Information
Gene Namesphingosine hydroxylase
Protein EntrySUR2_YEAST
UniProt IDP38992
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionRequired for hydroxylation of C-4 in the sphingoid moiety of ceramide. Involved in the response to syringomycin. {ECO:0000269|PubMed:9368039, ECO:0000269|PubMed:9556590}.
MiscellaneousPresent with 54300 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayMembrane lipid metabolism; sphingolipid biosynthesis.
SimilarityBelongs to the sterol desaturase family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.