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LMPD Database

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LMP006990

UniProt Annotations

Entry Information

Gene Name	Arv1p
Protein Entry	ARV1_YEAST
UniProt ID	Q06541
Species	Yeast (S288c)

Comments

Comment type	Description
Function	Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes. Regulates also the sphingolipid metabolism. Required for growth during anaerobiosis and sterol uptake. {ECO:0000269\|PubMed:11063737, ECO:0000269\|PubMed:12145310}.
Interaction	Q12007:ERR1; NbExp=1; IntAct=EBI-31952, EBI-35679;
Similarity	Belongs to the ARV1 family. {ECO:0000305}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269\|PubMed:12145310}; Multi-pass membrane protein {ECO:0000269\|PubMed:12145310}. Golgi apparatus membrane {ECO:0000269\|PubMed:12145310}; Multi-pass membrane protein {ECO:0000269\|PubMed:12145310}.