LMPD Database

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LMP007034

UniProt Annotations

Entry Information
Gene Namecardiolipin synthase
Protein EntryCRD1_YEAST
UniProt IDQ07560
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic Activity2 Phosphatidylglycerol = diphosphatidylglycerol + glycerol.
CautionRef.3 sequence was originally thought to originate from Mycobacterium phlei. {ECO:0000305}.
CofactorName=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Note=Divalent metal ions.;
FunctionCatalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
MiscellaneousPresent with 876 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the CDP-alcohol phosphatidyltransferase class-I family. {ECO:0000305}.
Subcellular LocationMitochondrion inner membrane; Multi-pass membrane protein.