LMPD Database

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LMP007063

UniProt Annotations

Entry Information
Gene Namebifunctional urea carboxylase/allophanate hydrolase
Protein EntryDUR1_YEAST
UniProt IDP32528
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityATP + urea + HCO(3)(-) = ADP + phosphate + urea-1-carboxylate.
Catalytic ActivityUrea-1-carboxylate + H(2)O = 2 CO(2) + 2 NH(3).
CofactorName=biotin; Xref=ChEBI:CHEBI:57586; Note=Biotin.;
FunctionHydrolysis of urea to ammonia and CO(2).
InductionBy allophanate or its non-metabolized analog oxalurate. Repressed in the presence of readily used nitrogen sources.
MiscellaneousPresent with 952 molecules/cell in log phase SD medium
MiscellaneousPresent with 952 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayNitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (allophanate route): step 1/2.
PathwayNitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (allophanate route): step 2/2.
SimilarityContains 1 ATP-grasp domain. {ECO:0000255|PROSITE- ProRule:PRU00409}.
SimilarityContains 1 biotin carboxylation domain
SimilarityContains 1 biotin carboxylation domain. {ECO:0000305}.
SimilarityContains 1 biotinyl-binding domain
SimilarityContains 1 biotinyl-binding domain. {ECO:0000255|PROSITE-ProRule:PRU01066, ECO:0000305}.
SubunitMonomer.