LMPD Database

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LMP007080

UniProt Annotations

Entry Information
Gene NameNsg1p
Protein EntryNSG1_YEAST
UniProt IDP38837
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionStabilizes the HMG-CoA reductase HMG2 by preventing its HRD1-dependent degradation. Binds directly to the sterol-sensing domain (SSD)-containing transmembrane region of HMG2, promoting its folding to protect it from degradation. {ECO:0000269|PubMed:16270032}.
MiscellaneousPresent with 1900 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityTo yeast YNL156c. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:16270032}; Multi-pass membrane protein {ECO:0000269|PubMed:16270032}.