LMPD Database

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LMP007086

UniProt Annotations

Entry Information
Gene Namesphinganine-1-phosphate aldolase DPL1
Protein EntrySGPL_YEAST
UniProt IDQ05567
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivitySphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde. {ECO:0000269|PubMed:20696404}.
CofactorName=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; Evidence={ECO:0000269|PubMed:20696404};
FunctionCleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. {ECO:0000269|PubMed:20696404, ECO:0000269|PubMed:9334171}.
MiscellaneousPresent with 13100 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayLipid metabolism; sphingolipid metabolism.
SimilarityBelongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily. {ECO:0000305}.
SubunitHomodimer. {ECO:0000269|PubMed:20696404}.