LMPD Database

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LMP007091

UniProt Annotations

Entry Information
Gene NameGpi18p
Protein EntryGPI18_YEAST
UniProt IDP38211
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionMannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly. {ECO:0000269|PubMed:15623507, ECO:0000269|PubMed:15720390, ECO:0000269|PubMed:17615295}.
InteractionP36156:ECM4; NbExp=1; IntAct=EBI-21377, EBI-2042717; P40540:KRE27; NbExp=1; IntAct=EBI-21377, EBI-24977; P38800:YHR080C; NbExp=1; IntAct=EBI-21377, EBI-24597;
PathwayGlycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
SimilarityBelongs to the PIGV family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:17615295}; Multi-pass membrane protein {ECO:0000269|PubMed:17615295}.
SubunitPart of the GPI mannosyltransferase 2 complex composed of GPI18 and PGA1.