LMPD Database

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LMP007160

UniProt Annotations

Entry Information
Gene Namecarnitine O-acetyltransferase CAT2
Protein EntryCACP_YEAST
UniProt IDP32796
SpeciesYeast (S288c)
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative initiation; Named isoforms=2; Name=Mitochondrial; IsoId=P32796-1; Sequence=Displayed; Name=Peroxisomal; IsoId=P32796-2; Sequence=VSP_018690; Note=Produced by alternative initiation at Met-23 of isoform Mitochondrial.;
Catalytic ActivityAcetyl-CoA + carnitine = CoA + O- acetylcarnitine.
FunctionCarnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.
InductionBy ethanol. Repressed by galactose.
InteractionSelf; NbExp=1; IntAct=EBI-3935, EBI-3935; Q07732:ADY3; NbExp=1; IntAct=EBI-3935, EBI-33406; Q02821:SRP1; NbExp=1; IntAct=EBI-3935, EBI-1797;
MiscellaneousPresent with 450 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the carnitine/choline acetyltransferase family. {ECO:0000305}.
Subcellular LocationIsoform Mitochondrial: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Subcellular LocationIsoform Peroxisomal: Peroxisome.