LMPD Database

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LMP007167

UniProt Annotations

Entry Information
Gene NameSps19p
Protein EntrySPS19_YEAST
UniProt IDP32573
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityTrans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH
Catalytic ActivityTrans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH. {ECO:0000269|PubMed:9268358}.
Developmental StageSequentially activated during the process of meiosis and spore formation.
FunctionAuxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Dispensable for growth and sporulation on solid acetate and oleate media, but is essential for these processes to occur on petroselineate.
InductionBy oleate. Transcription is regulated by the transcription factors PIP2, OAF1 and ADR1. Weakly induced during sporulation in diploid cells. {ECO:0000269|PubMed:11170837, ECO:0000269|PubMed:9268358, ECO:0000269|PubMed:9427398}.
Sequence CautionSequence=AAA62403.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAT93138.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAA55506.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAA96103.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Sequence CautionSequence=AAA62403.1; Type=Erroneous initiation; Evidence= ; Sequence=AAT93138.1; Type=Erroneous initiation; Evidence= ; Sequence=CAA55506.1; Type=Erroneous initiation; Evidence= ; Sequence=CAA96103.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family. {ECO:0000305}.
Subcellular LocationPeroxisome .
Subcellular LocationPeroxisome {ECO:0000269|PubMed:9268358}.
SubunitHomodimer
SubunitHomodimer. {ECO:0000269|PubMed:9268358}.