LMPD Database

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LMP007205

UniProt Annotations

Entry Information
Gene Name1-phosphatidylinositol-4-phosphate 5-kinase
Protein EntryMSS4_YEAST
UniProt IDP38994
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityATP + 1-phosphatidyl-1D-myo-inositol 4- phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
FunctionCatalyzes the phosphorylation of phosphatidylinositol 4- phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate. Acts downstream of STT4, but in a pathway that does not involve PKC1. May be involved in the organization of the actin cytoskeleton.
SimilarityContains 1 PIPK domain. {ECO:0000255|PROSITE- ProRule:PRU00781}.