LMPD Database

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LMP007268

UniProt Annotations

Entry Information
Gene NameScs2p
Protein EntrySCS2_YEAST
UniProt IDP40075
SpeciesYeast (S288c)
Comments
Comment typeDescription
DomainThe MSP domain is required for binding to the FFAT motif of target proteins.
FunctionTargets proteins containing a FFAT motif to endoplasmic reticulum membranes. Regulates phospholipid biosynthesis by modulating the subcellular localization of the transcriptional repressor OPI1. {ECO:0000269|PubMed:12727870, ECO:0000269|PubMed:15668246}.
MiscellaneousPresent with 3497 molecules/cell in log phase SD medium
MiscellaneousPresent with 3497 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the VAMP-associated protein (VAP) (TC 9.B.17) family
SimilarityBelongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. {ECO:0000305}.
SimilarityContains 1 MSP domain. {ECO:0000255|PROSITE- ProRule:PRU00132}.
Subcellular LocationEndoplasmic reticulum membrane; Single-pass type IV membrane protein. Nucleus membrane; Single-pass type IV membrane protein.
SubunitInteracts with OPI1. {ECO:0000269|PubMed:12727870, ECO:0000269|PubMed:15455074}.