LMPD Database

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LMP007318

UniProt Annotations

Entry Information
Gene NamePgc1p
Protein EntryPGC1_YEAST
UniProt IDQ08959
SpeciesYeast (S288c)
Comments
Comment typeDescription
Disruption PhenotypeLeads to the accumulation of phosphatidyl glycerol. {ECO:0000269|PubMed:18434318}.
FunctionPhosphatidylglycerol phospholipase required for the removal of excess phosphatidylglycerol (PG) via a phospholipase C- type degradation mechanism. {ECO:0000269|PubMed:16172116, ECO:0000269|PubMed:18434318}.
MiscellaneousPresent with 3270 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the glycerophosphoryl diester phosphodiesterase family. {ECO:0000305}.
SimilarityContains 1 GP-PDE domain. {ECO:0000305}.
Subcellular LocationMitochondrion membrane {ECO:0000269|PubMed:12514182, ECO:0000269|PubMed:14576278, ECO:0000269|PubMed:16823961, ECO:0000269|PubMed:18434318}; Single- pass type IV membrane protein {ECO:0000269|PubMed:12514182, ECO:0000269|PubMed:14576278, ECO:0000269|PubMed:16823961, ECO:0000269|PubMed:18434318}.