LMPD Database

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LMP007341

UniProt Annotations

Entry Information
Gene Nameputative dodecenoyl-CoA isomerase DCI1
Protein EntryDCI1_YEAST
UniProt IDQ08558
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionConverts 3,5-dienoyl-CoAs to the corresponding 2,4- dienoyl-CoAs. Involved in fatty acid metabolism. Required for ECI1 to be peroxisomal located. {ECO:0000269|PubMed:10381339, ECO:0000269|PubMed:10455114, ECO:0000269|PubMed:11302517}.
InductionBy oleate, through the binding of the OAF1-PIP2 transcriptional activator complex to its promoter ORE element. Expression is also induced during ammonia pulses in yeast colonies, at the beginning of detectable ammonia production. {ECO:0000269|PubMed:10455114, ECO:0000269|PubMed:10639339, ECO:0000269|PubMed:12429834, ECO:0000269|PubMed:9774671}.
PathwayLipid metabolism; fatty acid beta-oxidation.
SimilarityBelongs to the enoyl-CoA hydratase/isomerase family. {ECO:0000305}.
Subcellular LocationPeroxisome {ECO:0000269|PubMed:10381339, ECO:0000269|PubMed:10455114, ECO:0000269|PubMed:10639339}.
SubunitInteracts with ECI1. {ECO:0000269|PubMed:10381339}.