LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP007410

UniProt Annotations

Entry Information
Gene NameGpi16p
Protein EntryGPI16_YEAST
UniProt IDP38875
SpeciesYeast (S288c)
Comments
Comment typeDescription
CautionIt is uncertain whether Met-1 or Met-9 is the initiator. {ECO:0000305}.
FunctionComponent of the GPI transamidase complex. Involved in transfer of GPI to proteins. {ECO:0000269|PubMed:11483512, ECO:0000269|PubMed:11598210}.
InteractionP39012:GAA1; NbExp=3; IntAct=EBI-24869, EBI-7252; P49018:GPI8; NbExp=3; IntAct=EBI-24869, EBI-7822;
MiscellaneousPresent with 1680 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayGlycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
PtmThe disulfide bond between GPI8 and GPI16 is important for normal enzyme activity. {ECO:0000250}.
Sequence CautionSequence=AAB68365.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the PIGT family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:11598210}; Single-pass type I membrane protein {ECO:0000269|PubMed:11598210}.
SubunitForms a complex with CDC91, GPI17, GPI8 and GAA1. {ECO:0000269|PubMed:11598210}.