LMPD Database

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LMP007475

UniProt Annotations

Entry Information
Gene Namedodecenoyl-CoA isomerase
Protein EntryECI1_YEAST
UniProt IDQ05871
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic Activity(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl- CoA.
FunctionEssential for the beta oxidation of unsaturated fatty acids. {ECO:0000269|PubMed:9837886}.
InductionBy oleate. {ECO:0000269|PubMed:9837886}.
PathwayLipid metabolism; fatty acid beta-oxidation.
SimilarityBelongs to the enoyl-CoA hydratase/isomerase family. {ECO:0000305}.
Subcellular LocationPeroxisome {ECO:0000269|PubMed:10381339, ECO:0000269|PubMed:11302517, ECO:0000269|PubMed:9837886}. Note=This location is DCI1 dependent.
SubunitHomohexamer, dimer of trimers. Interacts with DCI1. {ECO:0000269|PubMed:10381339, ECO:0000269|PubMed:10944342, ECO:0000269|PubMed:11399063, ECO:0000269|PubMed:14741345}.