LMPD Database

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LMP007551

UniProt Annotations

Entry Information
Gene Namephosphatidylserine decarboxylase
Protein EntryPSD_ECOLI
UniProt IDP0A8K1
SpeciesE. coli
Comments
Comment typeDescription
Biophysicochemical PropertiespH dependence: Optimum pH is 6.5-7.5. {ECO:0000269|PubMed:4598120};
Catalytic ActivityPhosphatidyl-L-serine = phosphatidylethanolamine + CO(2). {ECO:0000269|PubMed:4598120}.
CofactorName=pyruvoyl group; Xref=ChEBI:CHEBI:45360; Evidence={ECO:0000269|PubMed:3042771};
Enzyme RegulationInhibited by ionic detergents such as Barlox- 12, an amine oxide, and sodium dodecyl sulfate. {ECO:0000269|PubMed:4598120}.
PathwayPhospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. {ECO:0000269|PubMed:4598120}.
PtmIs synthesized initially as an inactive proenzyme, which is activated by cleavage to produce a beta chain and an alpha chain. {ECO:0000269|PubMed:3042771}.
SimilarityBelongs to the phosphatidylserine decarboxylase family. Type 1 subfamily. {ECO:0000305}.
Subcellular LocationCell membrane {ECO:0000269|PubMed:4598120}; Peripheral membrane protein {ECO:0000269|PubMed:4598120}.
SubunitMultimer of the heterodimer. {ECO:0000269|PubMed:3042771}.