LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP007552

UniProt Annotations

Entry Information
Gene Namephosphatidylglycerol kinase, metal-dependent
Protein EntryYEGS_ECOLI
UniProt IDP76407
SpeciesE. coli
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=0.7 mM for phosphatidylglycerol; Vmax=29.7 nmol/min/mg enzyme; pH dependence: Optimum pH is 7.5. Active from pH 5 to 9.;
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:17351295}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000269|PubMed:17351295}; Note=Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute. {ECO:0000269|PubMed:17351295};
FunctionIn vitro phosphorylates phosphatidylglycerol but not diacylglycerol; the in vivo substrate is unknown.
InteractionP0ABH7:gltA; NbExp=2; IntAct=EBI-1127478, EBI-547808;
SimilarityBelongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily. {ECO:0000305}.
SimilarityContains 1 DAGKc domain. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000269|PubMed:17351295}.
SubunitMonomer. {ECO:0000269|PubMed:16511327, ECO:0000269|PubMed:17351295}.