LMPD Database

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LMP007665

UniProt Annotations

Entry Information
Gene Nameputative acetyl-CoA:acetoacetyl-CoA transferase: alpha subunit/beta subunit
Protein EntryYDIF_ECOLI
UniProt IDP37766
SpeciesE. coli
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + acetate = a fatty acid anion + acetyl-CoA.
FunctionCoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. May play a role in short-chain fatty acid metabolism in E.coli (By similarity). {ECO:0000250}.
MiscellaneousFormation of the covalent enzyme-CoA thioester intermediate proceeds via an unstable anhydride species formed between the carboxylate group of the catalytic glutamate of the enzyme and the carbonyl carbon of the thioester linkage of the substrate. {ECO:0000250}.
SimilarityBelongs to the 3-oxoacid CoA-transferase family. {ECO:0000305}.
SubunitHomotetramer; dimer of dimers. {ECO:0000250}.