LMPD Database

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LMP007725

UniProt Annotations

Entry Information
Gene Namemurein lipoprotein
Protein EntryLPP_ECOLI
UniProt IDP69776
SpeciesE. coli
Comments
Comment typeDescription
FunctionInteracts with the peptidoglycan both covalently and noncovalently. This interaction contributes to the maintenance of the structural and functional integrity of the cell envelope.
InteractionSelf; NbExp=2; IntAct=EBI-909750, EBI-909750; P02929:tonB; NbExp=2; IntAct=EBI-909750, EBI-6399993;
MiscellaneousAbout one-third of Lpp is covalently bound to peptidoglycan.
SimilarityBelongs to the Lpp family. {ECO:0000305}.
Subcellular LocationCell outer membrane; Lipid-anchor. Cell outer membrane; Peptidoglycan-anchor. Note=Found in the inner leaflet of the outer membrane. Targeted by the SRP/Sec/YidC pathway.
SubunitHomotrimer. Seems to interact with TolB, Pal and TonB. Has been isolated from outer membrane preparations as an approximately 87 kDa complex, suggesting it also forms larger complexes. {ECO:0000269|PubMed:10843861, ECO:0000269|PubMed:16079137, ECO:0000269|PubMed:3013869}.