LMPD Database

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LMP007730

UniProt Annotations

Entry Information
Gene Name3-oxoacyl-[acyl-carrier-protein] synthase II
Protein EntryFABF_ECOLI
UniProt IDP0AAI5
SpeciesE. coli
Comments
Comment typeDescription
Catalytic Activity(Z)-hexadec-11-enoyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl- carrier-protein] + CO(2) + [acyl-carrier-protein]. {ECO:0000269|PubMed:9013860}.
FunctionCatalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthesis. {ECO:0000269|PubMed:6988423, ECO:0000269|PubMed:9013860}.
InteractionP0A6Y8:dnaK; NbExp=2; IntAct=EBI-542783, EBI-542092;
PathwayLipid metabolism; fatty acid biosynthesis.
SimilarityBelongs to the beta-ketoacyl-ACP synthases family. {ECO:0000305}.
SubunitHomodimer.