LMPD Database

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LMP007735

UniProt Annotations

Entry Information
Gene Name3-oxoacyl-[acyl-carrier-protein] synthase I
Protein EntryFABB_ECOLI
UniProt IDP0A953
SpeciesE. coli
Comments
Comment typeDescription
Catalytic ActivityAcyl-[acyl-carrier-protein] + malonyl-[acyl- carrier-protein] = 3-oxoacyl-[acyl-carrier-protein] + CO(2) + [acyl-carrier-protein].
FunctionCatalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids. {ECO:0000269|PubMed:3076377}.
PathwayLipid metabolism; fatty acid biosynthesis.
SimilarityBelongs to the beta-ketoacyl-ACP synthases family. {ECO:0000305}.
Subcellular LocationCytoplasm.
SubunitHomodimer.