LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP007792

UniProt Annotations

Entry Information
Gene NameProtein SMS-1
Protein EntryQ9U3D4_CAEEL
UniProt IDQ9U3D4
SpeciesC. elegans
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=b {ECO:0000305}; IsoId=Q9U3D4-1; Sequence=Displayed; Note=No experimental confirmation available. {ECO:0000305}; Name=a {ECO:0000305}; IsoId=Q9U3D4-2; Sequence=VSP_050674; Note=No experimental confirmation available. {ECO:0000305}; Name=c; IsoId=Q9U3D4-3; Sequence=VSP_039807; Note=No experimental confirmation available.;
Catalytic ActivityA ceramide + a phosphatidylcholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol. {ECO:0000269|PubMed:14685263}.
FunctionSphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. {ECO:0000269|PubMed:14685263}.
PathwayLipid metabolism; sphingolipid metabolism. {ECO:0000269|PubMed:14685263}.
SimilarityBelongs to the sphingomyelin synthase family. {ECO:0000305}.
Subcellular LocationGolgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.