LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP007809

UniProt Annotations

Entry Information
Gene NameProtein SMS-2
Protein EntryQ20735_CAEEL
UniProt IDQ20735
SpeciesC. elegans
Comments
Comment typeDescription
Catalytic ActivityA ceramide + a phosphatidylcholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol.
FunctionSphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide.
PathwayLipid metabolism; sphingolipid metabolism.
SimilarityBelongs to the sphingomyelin synthase family.
Subcellular LocationMembrane ; Multi-pass membrane protein .