LMPD Database

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LMP007866

UniProt Annotations

Entry Information
Gene NameProtein PDHB-1
Protein EntryO44451_CAEEL
UniProt IDO44451
SpeciesC. elegans
Comments
Comment typeDescription
Catalytic ActivityPyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO(2).
CofactorName=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence= ;
FunctionThe pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
Subcellular LocationMitochondrion matrix .
SubunitTetramer of 2 alpha and 2 beta subunits.