LMPD Database

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LMP007890

UniProt Annotations

Entry Information
Gene NameProtein MOM-1
Protein EntryQ22329_CAEEL
UniProt IDQ22329
SpeciesC. elegans
Comments
Comment typeDescription
Disruption PhenotypeDefects in endoderm development, blastomere differentiation and mitotic spindle axis formation.
FunctionImplicated in the Wnt signaling pathway. Thought to be involved in lipid modification of Wnt proteins. Has a role in cell specification, specifically in blastomere signaling. Involved in cytosketetal polarity. Required for the orientation of mitotic spindle axis. {ECO:0000269|PubMed:10444600, ECO:0000269|PubMed:15020416, ECO:0000269|PubMed:9288750}.
SimilarityBelongs to the membrane-bound acyltransferase family. Porcupine subfamily.
Subcellular LocationMembrane ; Multi-pass membrane protein .