LMPD Database

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LMP007963

UniProt Annotations

Entry Information
Gene NameProtein MMCM-1
Protein EntryMUTA_CAEEL
UniProt IDQ23381
SpeciesC. elegans
Comments
Comment typeDescription
Catalytic Activity(R)-methylmalonyl-CoA = succinyl-CoA.
CofactorName=adenosylcob(III)alamin; Xref=ChEBI:CHEBI:18408; Evidence={ECO:0000250};
FunctionInvolved, in man, in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species (By similarity). {ECO:0000250}.
SimilarityBelongs to the methylmalonyl-CoA mutase family. {ECO:0000305}.
SimilarityContains 1 B12-binding domain. {ECO:0000255|PROSITE- ProRule:PRU00666}.
Subcellular LocationMitochondrion matrix {ECO:0000250}.
SubunitHomodimer. {ECO:0000250}.