LMPD Database

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LMP008041

UniProt Annotations

Entry Information
Gene NameProtein GLY-13
Protein EntryMGAT1_CAEEL
UniProt IDQ11068
SpeciesC. elegans
Comments
Comment typeDescription
Catalytic ActivityUDP-N-acetyl-D-glucosamine + 3-(alpha-D- mannosyl)-beta-D-mannosyl-R = UDP + 3-(2-(N-acetyl-beta-D- glucosaminyl)-alpha-D-mannosyl)-beta-D-mannosyl-R.
CofactorName=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Note=The cofactor is mostly bound to the substrate. {ECO:0000250};
Developmental StageExpressed throughout development. {ECO:0000269|PubMed:9867843}.
FunctionInitiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans (By similarity). {ECO:0000250}.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 13 family. {ECO:0000305}.
Subcellular LocationGolgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.