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LMPD Database

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LMP008312

UniProt Annotations

Entry Information

Gene Name	Protein LBP-1
Protein Entry	FABP1_CAEEL
UniProt ID	Q20223
Species	C. elegans

Comments

Comment type	Description
Domain	Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior. {ECO:0000250}.
Function	May play a role in sequestering potentially toxic fatty acids and their peroxidation products, or it may be involved in the maintenance of the impermeable lipid layer of the eggshell. {ECO:0000269\|PubMed:10693745}.
Similarity	Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. {ECO:0000305}.
Subcellular Location	Secreted {ECO:0000269\|PubMed:10693745}. Note=From the hypodermis into the perivitelline fluid of the developing embryo prior to hatching.
Tissue Specificity	First detected in hypodermal precursor cells at the time of gastrulation. From the two-fold stage through to three-fold stages, expression is localized exclusively to hyp-7 but disappears in newly hatched L1s and subsequent developmental stages. Expression from L1 to adult stages is found in a single neuron in the ventral cord with a process into the nerve ring. {ECO:0000269\|PubMed:10693745}.