LMPD Database

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LMP009062

UniProt Annotations

Entry Information
Gene NameHormone receptor-like in 39
Protein EntryFTF1B_DROME
UniProt IDQ05192
SpeciesDrosophila
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=A; Synonyms=B; IsoId=Q05192-1; Sequence=Displayed; Name=C; Synonyms=DHR39-short; IsoId=Q05192-2; Sequence=VSP_003718, VSP_003719;
Developmental StageExpressed at all stages. {ECO:0000269|PubMed:8382937, ECO:0000269|PubMed:8479913}.
FunctionActs as a cofactor to fushi tarazu (ftz). Facilitates the binding of ftz to DNA. Binds the sequence element 5'- YCYYGGYCR-3' in the zebra element of ftz. Probably also functions as a receptor for a yet unknown ligand. {ECO:0000269|PubMed:8164672, ECO:0000269|PubMed:8382937, ECO:0000269|PubMed:8479913}.
InteractionQ86BY9:rig; NbExp=2; IntAct=EBI-75048, EBI-422757; O96757:stumps; NbExp=3; IntAct=EBI-75048, EBI-74922;
SimilarityBelongs to the nuclear hormone receptor family. NR5 subfamily. {ECO:0000305}.
SimilarityContains 1 nuclear receptor DNA-binding domain. {ECO:0000255|PROSITE-ProRule:PRU00407}.
Subcellular LocationNucleus.
SubunitMonomer; forms a complex with ftz. {ECO:0000250}.
Tissue SpecificityExpressed throughout the blastodermal layer in early embryos. At later stages, strong expression is observed in the brain, ventral cord and hindgut. {ECO:0000269|PubMed:8382937, ECO:0000269|PubMed:8479913}.