LMPD Database

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LMP009682

UniProt Annotations

Entry Information
Gene Name3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2
Protein EntryHSDD2_ARATH
UniProt IDQ67ZE1
SpeciesArabidopsis
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q67ZE1-1; Sequence=Displayed; Note=Constructed according to the conserved gene model. No experimental confirmation available.; Name=2; IsoId=Q67ZE1-2; Sequence=VSP_037004, VSP_037005; Note=May be due to an intron retention. No experimental confirmation available.; Name=3; IsoId=Q67ZE1-3; Sequence=VSP_037003; Note=May be due to a competing acceptor splice site. No experimental confirmation available.;
Catalytic ActivityA 3-beta-hydroxysteroid-4-alpha-carboxylate + NAD(P)(+) = a 3-oxosteroid + CO(2) + NAD(P)H.
PathwaySteroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 4/6.
Sequence CautionSequence=BX818951; Type=Frameshift; Positions=283; Evidence={ECO:0000305};
SimilarityBelongs to the 3-beta-HSD family. {ECO:0000305}.
SimilarityContains 1 reticulon domain. {ECO:0000255|PROSITE- ProRule:PRU00170}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.