LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP009775

UniProt Annotations

Entry Information
Gene Nameacyl-CoA binding protein 1
Protein EntryACBP1_ARATH
UniProt IDQ9SM23
SpeciesArabidopsis
Comments
Comment typeDescription
Developmental StageExpressed in embryos at the cotyledons, hypocotyls, procambiums, especially in epidermal cells and axis. {ECO:0000269|PubMed:10363372}.
Disruption PhenotypeIncreased sensitivity to lead ions. {ECO:0000269|PubMed:18182029}.
FunctionBinds medium- and long-chain acyl-CoA esters with very high affinity. Can interact in vitro with arachidonyl-CoA, barely with oleoyl-CoA, but not with palmitoyl-CoA. Confers tolerance and binds to lead ions Pb(2+), probably by promoting lead translocation from roots to shoots. May function as an intracellular carrier of acyl-CoA esters (By similarity). {ECO:0000250}.
InductionIn roots by lead. {ECO:0000269|PubMed:18182029}.
PtmGlycosylated. In seeds, localized in the outer integument. {ECO:0000269|PubMed:9862500}.
SimilarityBelongs to the ACBP family. {ECO:0000305}.
SimilarityContains 1 ACB (acyl-CoA-binding) domain. {ECO:0000255|PROSITE-ProRule:PRU00573}.
SimilarityContains 3 ANK repeats. {ECO:0000255|PROSITE- ProRule:PRU00023}.
Subcellular LocationCell membrane; Single-pass membrane protein. Secreted, cell wall. Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Detected in the cell walls of the outer integument cells at the seed coat.
SubunitInteracts with RAP2-12. {ECO:0000269|PubMed:22020282}.
Tissue SpecificityExpressed at low levels in roots, stems, leaves, flowers, and siliques, especially within seeds. {ECO:0000269|PubMed:9862500, ECO:0000269|Ref.9}.