LMPD Database

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LMP009776

UniProt Annotations

Entry Information
Gene Nameacyl-CoA binding protein 2
Protein EntryACBP2_ARATH
UniProt IDQ9STP8
SpeciesArabidopsis
Comments
Comment typeDescription
FunctionBinds medium- and long-chain acyl-CoA esters with very high affinity. Can interact in vitro with palmitoyl-CoA, but not with oleoyl-CoA. Binds to lead ions (Pb). May function as an intracellular carrier of acyl-CoA esters. Required for proper phospholipid and, to a lower extent, galactolipid composition. {ECO:0000269|PubMed:11202434, ECO:0000269|PubMed:15604682, ECO:0000269|PubMed:18182029, ECO:0000269|Ref.2}.
InductionIn roots by lead. {ECO:0000269|PubMed:18182029}.
InteractionQ9SZN7:HIPP26; NbExp=5; IntAct=EBI-368234, EBI-2008207; P42736:RAP2-3; NbExp=3; IntAct=EBI-368234, EBI-368243;
SimilarityBelongs to the ACBP family. {ECO:0000305}.
SimilarityContains 1 ACB (acyl-CoA-binding) domain. {ECO:0000255|PROSITE-ProRule:PRU00573}.
SimilarityContains 2 ANK repeats. {ECO:0000255|PROSITE- ProRule:PRU00023}.
Subcellular LocationCell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.
SubunitInteracts (via ankyrin repeats) with HIPP26 and the ethylene-responsive element-binding proteins RAP2-3/EBP and RAP2- 12. Interacts with CSE. {ECO:0000269|PubMed:15159625, ECO:0000269|PubMed:18823312, ECO:0000269|PubMed:20345607, ECO:0000269|PubMed:22020282}.
Tissue SpecificityMostly expressed in roots and flowers, and, to a lower extent, in stems, pods and leaves (at protein level). {ECO:0000269|PubMed:11202434, ECO:0000269|Ref.2}.